{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride
{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride
CAS: 1017428-21-5
Molecular Formula: C12H18N2
{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride - Names and Identifiers
{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride - Physico-chemical Properties
| Molecular Formula | C12H18N2 |
| Molar Mass | 190.28 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD18205894 |
{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride - Risk and Safety
| Hazard Class | IRRITANT |
{[1-(4-Methylphenyl)pyrrolidin-3-yl]methyl}amine hydrochloride - Introduction
[{[1-(4-Methylphenyl) pyrrolidin-3-yl] methyl} amine hydrochloride] is an organic compound having the chemical formula C14H20ClN.
Nature:
-Appearance: White crystalline solid
-Solubility: Good solubility in water and organic solvents
-Flash point: approx. 118°C
-Melting point: approximately 228-232°C
Use:
This compound is an important organic synthesis intermediate that can be used to prepare other compounds, such as drugs or dominant dyes.
Preparation Method:
{[1-(4-Methylphenyl) pyrrolidin-3-yl] methyl} amine hydrochloride can be synthesized by the following steps:
1.1-pyrrolidine formaldehyde reacts with 4-methyl aniline to generate 1-(4-methyl phenyl) pyrrolidine -3-formaldehyde.
2.1-(4-methyl phenyl) pyrrolidine -3-formaldehyde is reacted with acetyl chloride to generate 1-(4-methyl phenyl) pyrrolidine -3-acetic acid.
3. The reaction of 1-(4-methylphenyl) pyrrolidine-3-acetic acid with aqueous ammonia produces {[1-(4-methylphenyl) pyrrolidin-3-yl] methyl} amine.
4. Finally, {[1-(4-methylphenyl) pyrrolidin-3-yl] methyl} amine is reacted with hydrochloric acid to form the corresponding hydrochloride salt.
Safety Information:
-This compound may cause irritation to the eyes, skin and respiratory tract, so proper safety measures need to be taken when handling.
-Wear appropriate protective gloves and eye protection when preparing or handling the compound.
-It should be operated in a well-ventilated place to avoid inhaling dust or gas.
-If you are exposed to or inhaled the compound, please seek medical help immediately and provide detailed information about the compound.
Nature:
-Appearance: White crystalline solid
-Solubility: Good solubility in water and organic solvents
-Flash point: approx. 118°C
-Melting point: approximately 228-232°C
Use:
This compound is an important organic synthesis intermediate that can be used to prepare other compounds, such as drugs or dominant dyes.
Preparation Method:
{[1-(4-Methylphenyl) pyrrolidin-3-yl] methyl} amine hydrochloride can be synthesized by the following steps:
1.1-pyrrolidine formaldehyde reacts with 4-methyl aniline to generate 1-(4-methyl phenyl) pyrrolidine -3-formaldehyde.
2.1-(4-methyl phenyl) pyrrolidine -3-formaldehyde is reacted with acetyl chloride to generate 1-(4-methyl phenyl) pyrrolidine -3-acetic acid.
3. The reaction of 1-(4-methylphenyl) pyrrolidine-3-acetic acid with aqueous ammonia produces {[1-(4-methylphenyl) pyrrolidin-3-yl] methyl} amine.
4. Finally, {[1-(4-methylphenyl) pyrrolidin-3-yl] methyl} amine is reacted with hydrochloric acid to form the corresponding hydrochloride salt.
Safety Information:
-This compound may cause irritation to the eyes, skin and respiratory tract, so proper safety measures need to be taken when handling.
-Wear appropriate protective gloves and eye protection when preparing or handling the compound.
-It should be operated in a well-ventilated place to avoid inhaling dust or gas.
-If you are exposed to or inhaled the compound, please seek medical help immediately and provide detailed information about the compound.
Last Update：2024-04-09 21:00:56
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